Platlet-Rich Plasma - Review of Literature

Nikolovska, Bisera; Miladinova, Daniela; Pejkova, Sofija; Trajkova, Andrijana; Georgieva, Gordana; Jovanoski, Tomislav; Jovanovska, Katerina

doi:10.2478/prilozi-2021-0011

Platlet-Rich Plasma - Review of Literature

Journal

Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)

Date Issued

2021-04-23

Author(s)

Trajkova, Andrijana

Georgieva, Gordana

Jovanoski, Tomislav

Jovanovska, Katerina

DOI

10.2478/prilozi-2021-0011

Abstract

Wound healing is a dynamic and physiological process for restoring the normal architecture and functionality of damaged tissue. Platelet-rich plasma (PRP) is an autologous whole blood product that contains a large number of platelets in a small volume of plasma with complete set of coagulation factors, which are in physiological concentrations. PRP has haemostatic, adhesive properties and acts supraphysiologically in the process of wound healing and osteogenesis. Platelets play a very important role in the wound healing process by providing growth factors that enhance the rate and quality of wound healing by many different mechanisms. The aim of this review is to describe: the biology of platelets and their role in the wound healing process, the terminology of platelet rich products, PRP preparation, activation and concentration of PRP, as well as the use of PRP in plastic surgery.